Nitrazolam
Not to be confused with nitrazepam.
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CAS Number | 28910-99-8 |
PubChem (CID) | 20317278 |
ChemSpider | 15387105 |
UNII | K499DBB308 |
Chemical and physical data | |
Formula | C17H13N5O2 |
Molar mass | 319.32 g·mol−1 |
3D model (Jmol) | Interactive image |
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Nitrazolam is a benzodiazepine[1] that has been sold online as a designer drug.[2][3]
It is closely related to clonazolam, only differing by the removal of a chlorine group at the benzene ring.
Animal studies indicate that nitrazolam can be several times more potent than diazepam as an antagonist of electroshock-induced tonic-extensor convulsions.[4]
See also
References
- ↑ Jackson B. Hester, Jr (19 October 1976). "Patent US3987052 - 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines". The Upjohn Company.
- ↑ "Nitrazolam". New Synthetic Drugs Database.
- ↑ Moosmann, Bjoern; Bisel, Philippe; Franz, Florian; Huppertz, Laura M.; Auwärter, Volker (2016). "Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines – an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam, and nitrazolam". Journal of Mass Spectrometry. doi:10.1002/jms.3840. ISSN 1096-9888. PMID 27535017 – via Wiley Online Library.
- ↑ Jackson B. Hester Jr.; Allan D. Rudzik; Bharat V. Kamdar (November 1971). "6-Phenyl-4H-s-triazolo[4,3-a] [1,4]benzodiazepines which have central nervous system depressant activity". Journal of Medicinal Chemistry. 14 (11): 1078–1081. doi:10.1021/jm00293a015. PMID 5165540.
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