Chloralose
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| Names | |
|---|---|
| IUPAC name
(5ξ)-1,2-O-[2,2,2-Trichloroethylidene]-α-xylo-hexofuranose | |
| Identifiers | |
15879-93-3  | |
| 3D model (Jmol) | Interactive image |
| 85418 | |
| ChEMBL | ChEMBL2104181 |
| ChemSpider | 5414376  |
| ECHA InfoCard | 100.036.363 |
| EC Number | 240-016-7 |
| KEGG | C18707 |
| MeSH | Chloralose |
| PubChem | 7057995 40467114 (2R,3aR,5R,6R)-6-hydroxy-2-methyl-furo-5-yl 27525 (2R,5R,6S,6aR)-6-hydroxy-2-methyl-furo-5-yl 16211632 (1R)-dioxol, (2R,5R,6S,6aR)-6-hydroxy-2-methyl-furo-5-yl 186624 (1R)-dioxol, (3aR,5R,6S,6aR)-6-hydroxy-furo-5-yl 2723807 (2R,3aR,5R,6S,6aR)-6-hydroxy-2-methyl-furo-5-yl 85991 |
| RTECS number | FM9450000 |
| UNII | 238BZ29MUE |
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| Properties | |
| C8H11Cl3O6 | |
| Molar mass | 309.52 g·mol−1 |
| Melting point | 176 to 182 °C (349 to 360 °F; 449 to 455 K) |
| Hazards | |
| Main hazards | Harmful if swallowed Harmful if inhaled |
| EU classification (DSD) |
 Xn |
| R-phrases | R20/22 |
| S-phrases | (S2) S16 S24/25 S28 |
| Related compounds | |
| Related compounds |
Chloral hydrate |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Chloralose is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative.[1] Its anesthetic action is due to positive allosteric agonism of the GABAA receptor, and as such is capable of affecting humans. Symptoms of exposure would be similar to the presentation of a benzodiazepine overdose and may be fatal (by means of respiratory arrest and subsequent hypoxia) but mechanical ventilation reduces the risk of death after exposure to near zero if medical assistance is obtained promptly.
Chemically, it is a chlorinated acetal derivative of glucose.
It is listed in Annex I of Directive 67/548/EEC with the classification Harmful (Xn)