11-Ketodihydrotestosterone

11-Ketodihydrotestosterone

Names
IUPAC name (5S,8S,9S,10S,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
Other names 11-Oxodihydrotestosterone; 5α-Androstan-17β-ol-3,11-dione; 11-KDHT
Identifiers
CAS Number	32694-37-4
3D model (Jmol)	Interactive image
ChemSpider	9372548
PubChem	11197479
InChI InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h11,13-14,16-17,22H,3-10H2,1-2H3/t11-,13-,14-,16-,17+,18-,19-/m0/s1 Key: RSQKILYTRHKUIJ-HZGXJFKTSA-N
SMILES C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4O)C
Properties
Chemical formula	C19H28O3
Molar mass	304.43 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

11-Ketodihydrotestosterone (11-KDHT), also known as 5α-androstan-17β-ol-3,11-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands.^[1] It is closely related to 11β-hydroxyandrostenedione (11β-KA4), adrenosterone (11-ketoandrostenedione; 11-KA4), and 11-ketotestosterone (11-KT), which are also produced in the adrenal glands.^[1]

See also

• Dihydrotestosterone

References

1. Pretorius, Elzette; Arlt, Wiebke; Storbeck, Karl-Heinz (2016). "A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids". Molecular and Cellular Endocrinology. doi:10.1016/j.mce.2016.08.014. ISSN 0303-7207.