1,3-Dimethylbutylamine

1,3-Dimethylbutylamine
Names
Preferred IUPAC name
4-Methylpentan-2-amine
Other names
(4-Methylpentan-2-yl)amine
Identifiers
108-09-8 YesY
3D model (Jmol) Interactive image
ChemSpider 7620
ECHA InfoCard 100.003.227
PubChem 7908 CID 7908
UNII KXP599H5R6 YesY
Properties
C6H15N
Molar mass 101.19 g·mol−1
Density 0.717 g/mL[1]
Boiling point 108–110 °C (226–230 °F; 381–383 K)[1]
Hazards
NFPA 704
Flammability code 3: Liquids and solids that can be ignited under almost all ambient temperature conditions. Flash point between 23 and 38 °C (73 and 100 °F). E.g., gasoline) Health code 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g., chloroform Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
3
2
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

1,3-Dimethylbutylamine (1,3-DMBA), or simply dimethylbutylamine (DMBA), is a stimulant drug structurally related to methylhexanamine (1,3-dimethylamylamine (1,3-DMAA)) where a butyl group replaces the amyl group. It is also known as AMP Citrate (4-amino-2-methylpentane citrate). The compound is an aliphatic amine.

DMBA has been identified as an unapproved ingredient in some over-the-counter dietary supplements,[2][3][4] in which it is used in an apparent attempt to avoid laws prohibiting the use of methylhexanamine.[5] The U.S. Food and Drug Administration (FDA) considers any dietary supplement containing DMBA to be "adulterated".[6]

There are no known human safety studies on DMBA and its health effects are entirely unknown.[2][3][7]

References

  1. 1 2 "1,3-Dimethylbutylamine". Sigma-Aldrich.
  2. 1 2 Cohen, Pieter A.; Travis, John C.; Venhuis, Bastiaan J. (2015). "A synthetic stimulant never tested in humans, 1,3-dimethylbutylamine (DMBA), is identified in multiple dietary supplements". Drug Testing and Analysis. 7 (1): 83–7. doi:10.1002/dta.1735. PMID 25293509.
  3. 1 2 "Unapproved Synthetic Stimulant "DMBA" Found in Multiple Dietary Supplements". NSF International.
  4. "FDA Warns 14 Sports Supplement Companies Of Illegal DMBA (AMP Citrate)". Forbes. May 6, 2015.
  5. "Stimulant Potentially Dangerous to Health, FDA Warns". U.S. Food and Drug Administration. April 11, 2013. Retrieved March 10, 2015.
  6. "DMBA in Dietary Supplements". Food and Drug Administration.
  7. "Revealing the hidden dangers of dietary supplements". Science. 20 August 2015. doi:10.1126/science.aad1651.


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