SLC44A1

SLC44A1
Identifiers
Aliases	SLC44A1, CD92, CDW92, CHTL1, CTL1, solute carrier family 44 member 1
External IDs	MGI: 2140592 HomoloGene: 11137 GeneCards: SLC44A1
Gene ontology Molecular function • choline transmembrane transporter activity Cellular component • extracellular exosome • nucleoplasm • mitochondrion • plasma membrane • integral component of membrane • mitochondrial outer membrane • membrane Biological process • phosphatidylcholine biosynthetic process • transmembrane transport • transport • choline transport • choline catabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23446	100434
Ensembl	ENSG00000070214	ENSMUSG00000028412
UniProt	Q8WWI5	Q6X893
RefSeq (mRNA)	NM_001286730 NM_022109 NM_080546	NM_001159633 NM_133891
RefSeq (protein)	NP_001273659.1 NP_536856.2	NP_598652.3
Location (UCSC)	Chr 9: 105.24 – 105.44 Mb	Chr 4: 53.44 – 53.62 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Choline transporter-like protein 1 is a protein that in humans is encoded by the SLC44A1 gene.^[3][4][5]

See also

• Cluster of differentiation
• Solute carrier family

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H (November 2001). "Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells". Journal of Immunology. 167 (10): 5795–804. doi:10.4049/jimmunol.167.10.5795. PMID 11698453.
4. O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM (February 2000). "An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins". Proceedings of the National Academy of Sciences of the United States of America. 97 (4): 1835–40. doi:10.1073/pnas.030339697. PMC 26522. PMID 10677542.
5. "Entrez Gene: SLC44A1 solute carrier family 44, member 1".

Further reading

• Yuan Z, Tie A, Tarnopolsky M, Bakovic M (June 2006). "Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1". Physiological Genomics. 26 (1): 76–90. doi:10.1152/physiolgenomics.00107.2005. PMID 16609143.
• Fullerton MD, Wagner L, Yuan Z, Bakovic M (April 2006). "Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages". American Journal of Physiology. Cell Physiology. 290 (4): C1230–8. doi:10.1152/ajpcell.00255.2005. PMID 16319125.
• Li D, Wang F, Lai M, Chen Y, Zhang JF (February 2005). "A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C". The Journal of Neuroscience. 25 (8): 1914–23. doi:10.1523/JNEUROSCI.4790-04.2005. PMID 15728831.
• Traiffort E, Ruat M, O'Regan S, Meunier FM (March 2005). "Molecular characterization of the family of choline transporter-like proteins and their splice variants". Journal of Neurochemistry. 92 (5): 1116–25. doi:10.1111/j.1471-4159.2004.02962.x. PMID 15715662.
• Lecomte MJ, De Gois S, Guerci A, Ravassard P, Faucon Biguet N, Mallet J, Berrard S (February 2005). "Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia". Molecular and Cellular Neurosciences. 28 (2): 303–13. doi:10.1016/j.mcn.2004.09.014. PMID 15691711.
• Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P (December 2003). "Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3". Proceedings of the National Academy of Sciences of the United States of America. 100 (26): 16006–11. doi:10.1073/pnas.2136600100. PMC 307683. PMID 14663150.
• Takekawa M, Maeda T, Saito H (August 1998). "Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways". The EMBO Journal. 17 (16): 4744–52. doi:10.1093/emboj/17.16.4744. PMC 1170803. PMID 9707433.

External links

• SLC44A1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)