RFX3

RFX3
Identifiers
Aliases RFX3
External IDs MGI: 106582 HomoloGene: 7917 GeneCards: RFX3
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

5991

19726

Ensembl

ENSG00000080298

ENSMUSG00000040929

UniProt

P48380

P48381

RefSeq (mRNA)

NM_001282116
NM_001282117
NM_002919
NM_134428

NM_001166414
NM_011265

RefSeq (protein)

NP_001269045.1
NP_001269046.1
NP_002910.1
NP_602304.1

NP_001159886.1
NP_035395.2

Location (UCSC) Chr 9: 3.22 – 3.53 Mb Chr 19: 27.76 – 28.01 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.[3][4]

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.[4]

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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