ZNF281

ZNF281
Identifiers
Aliases	ZNF281, ZBP-99, ZNP-99, zinc finger protein 281
External IDs	MGI: 3029290 HomoloGene: 8270 GeneCards: ZNF281
Gene ontology Molecular function • sequence-specific DNA binding • DNA binding • core promoter binding • transcription corepressor activity • transcription factor activity, sequence-specific DNA binding • metal ion binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • protein binding • nucleic acid binding • transcription regulatory region DNA binding Cellular component • nucleoplasm • nucleus Biological process • cell differentiation • regulation of transcription, DNA-templated • embryonic body morphogenesis • negative regulation of transcription from RNA polymerase II promoter • negative regulation of gene expression • transcription, DNA-templated • stem cell differentiation • positive regulation of transcription, DNA-templated • negative regulation of transcription, DNA-templated Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23528	226442
Ensembl	ENSG00000162702	ENSMUSG00000041483
UniProt	Q9Y2X9	Q99LI5
RefSeq (mRNA)	NM_012482 NM_001281293 NM_001281294	NM_001160251 NM_177643
RefSeq (protein)	NP_001268222.1 NP_001268223.1 NP_036614.1	NP_001153723.1 NP_808311.1
Location (UCSC)	Chr 1: 200.4 – 200.41 Mb	Chr 1: 136.62 – 136.63 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Zinc finger protein 281 is a protein that in humans is encoded by the ZNF281 gene.^[3][4]

See also

• Zinc finger

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Law DJ, Du M, Law GL, Merchant JL (Sep 1999). "ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression". Biochem Biophys Res Commun. 262 (1): 113–120. doi:10.1006/bbrc.1999.1180. PMID 10448078.
4. "Entrez Gene: ZNF281 zinc finger protein 281".

Further reading

• Lisowsky T, Polosa PL, Sagliano A, et al. (1999). "Identification of human GC-box-binding zinc finger protein, a new Krüppel-like zinc finger protein, by the yeast one-hybrid screening with a GC-rich target sequence". FEBS Lett. 453 (3): 369–374. doi:10.1016/S0014-5793(99)00754-1. PMID 10405178.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• ZNF281 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.