SALL3

SALL3
Identifiers
Aliases	SALL3, ZNF796, spalt-like transcription factor 3, spalt like transcription factor 3
External IDs	MGI: 109295 HomoloGene: 18142 GeneCards: SALL3
Gene ontology Molecular function • transcription factor activity, sequence-specific DNA binding • transcription regulatory region DNA binding • sequence-specific DNA binding • DNA binding • metal ion binding • nucleic acid binding Cellular component • nucleus Biological process • forelimb morphogenesis • neurogenesis • regulation of transcription, DNA-templated • negative regulation of smoothened signaling pathway • transcription from RNA polymerase II promoter • olfactory bulb interneuron development • hindlimb morphogenesis • signal transduction • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	27164	20689
Ensembl	n/a	ENSMUSG00000024565
UniProt	Q9BXA9	Q62255
RefSeq (mRNA)	NM_171999	NM_178280
RefSeq (protein)	NP_741996.2	NP_840064.2
Location (UCSC)	Chr 18: 78.98 – 79 Mb	Chr 18: 80.97 – 80.99 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Sal-like protein 3, also known as zinc finger protein SALL3, is a protein that in humans in encoded by the SALL3 gene.^[3][4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: sal-like 3 (Drosophila)".
4. Kohlhase J, Hausmann S, Stojmenovic G, Dixkens C, Bink K, Schulz-Schaeffer W, Altmann M, Engel W (December 1999). "SALL3, a new member of the human spalt-like gene family, maps to 18q23". Genomics. 62 (2): 216–22. doi:10.1006/geno.1999.6005. PMID 10610715.

Further reading

• Sweetman D, Münsterberg A (2006). "The vertebrate spalt genes in development and disease.". Dev. Biol. 293 (2): 285–93. doi:10.1016/j.ydbio.2006.02.009. PMID 16545361.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Shikauchi Y, Saiura A, Kubo T, et al. (2009). "SALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinoma.". Mol. Cell. Biol. 29 (7): 1944–58. doi:10.1128/MCB.00840-08. PMC 2655625. PMID 19139273.
• Julií A; Ballina J; Caí±ete JD; et al. (2008). "Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.". Arthritis Rheum. 58 (8): 2275–86. doi:10.1002/art.23623. PMID 18668548.
• Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome.". Mol. Cell Proteomics. 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID 18029348.
• Jugessur A, Shi M, Gjessing HK, et al. (2010). "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.". PLoS ONE. 5 (7): e11493. doi:10.1371/journal.pone.0011493. PMC 2901336. PMID 20634891.
• de Celis JF, Barrio R (2009). "Regulation and function of Spalt proteins during animal development.". Int. J. Dev. Biol. 53 (8-10): 1385–98. doi:10.1387/ijdb.072408jd. PMID 19247946.